High-density storage at room-temperature using GenPlates
GenPlates are high-density room-temperature storage containers for biological samples preserved in the dry-state. GenPlates represent a proprietary format for storing and/or transporting biosamples at room temperature, in the dry-state. The biosample is embedded in FTA paper, which is a macroporous cellulose matrix that is chemically treated to inactivate bacteria and virus. Upon application of 10ul of biosample directly to the 6mm disc of FTA paper, cells lyse and release DNA. The DNA becomes entwined in the fibrous network of the cellulose matrix. The entwined biosample is dried completely at room temperature. The GenPlate with the dried sample is sealed with an adhesive cover and ready for storage or transport. When DNA is required for downstream analysis, high-quality double-stranded DNA from FTA and Guthrie paper can be reliably recovered using the GenSolve chemistry.
More than 18 years of data and analysis exist for DNA storage on FTA paper. The chemistry for recovering DNA from FTA paper has been thoroughly validated. DNA stored on and recovered from FTA paper has been reliably used in demanding downstream experiments such as Illumina and Affymetrix microarrays.
